Transmissible Spongiform
Encephalopathies (TSEs)

Bovine spongiform encephalopathy (BSE), chronic wasting disease (CWD) and scrapie belong to the family of transmissible spongiform encephalopathies (TSEs). Clinically affected animals exhibit ataxia and excessive salivation, along with other behavioral disturbances. These animals show a progressive loss of physical condition that precedes death. The modes of transmission and the causative agents of TSEs are poorly understood. The disease is characterized by accumulation of prion protein in the medulla oblongata (obex) region of the brain, as well as other tissues (lymph nodes, spleen, tonsils, etc.).

 
Transmissible Spongiform Encephalopathies (TSEs)

Testing Solutions†

HerdChek BSE Scrapie Ag Test

Availability/Distribution: Outside the U.S.

The HerdChek BSE-Scrapie Ag Test is an antigen-capture enzyme immunoassay (EIA) for the detection of the abnormal conformer of the prion protein (PrPSc) in bovine, caprine and ovine postmortem tissues.

 

BSE-Scrapie Ag Information Brochure  

BSE/BSE-Scrapie Protocol  

 

BSE Video: Learn how easy it is to run the HerdChek BSE-Scrapie Ag Test.
Low-Speed (dial-up modem) 
High-Speed (cable/ISDN/T1) 

Creating a UDA for the BSE--Scrapie Antigen Test Kit  

 

*Time to complete EIA portion of the test

HerdChek BSE-Scrapie Ag Test:

Part Number: 99-08600

  • 5 plates (strips)
  • obex, spleen and lymph node samples
  • very simple sample preparation and EIA protocol—no proteinase K digestion, less equipment required, less hands-on time, results in 90 minutes*
 

HerdChek CWD Ag Test

Availability/Distribution: Worldwide

The HerdChek CWD Ag Test is an antigen-capture enzyme immunoassay (EIA) for the detection of the abnormal conformer of the prion protein (PrPSc) in postmortem white-tailed and mule deer retropharyngeal lymph node tissue. Additional species elk claim is in the late stages of development.

HerdChek CWD Ag Test:

Part Number: 99-09663

  • 5 plates (strips)
  • retropharyngeal lymph node tissue samples
  • very simple sample preparation and EIA protocol—no proteinase K digestion, less equipment required, all room-temperature, less hands-on time, results in less than 3.5 hours
 

Pourquier® mAB 2G11

Availability/Distribution: Outside the U.S.

The Pourquier mAB 2G11

Pourquier* mAB 2G11:

Part Number: P01610
 

† Not all products are available and/or registered in every country.